& know how
From bioinformatics to fermentation technology, discover our core competences
We hold cutting-edge expertise in the architecture of microorganism metabolism and all the tools necessary to implement it, with an approach that integrates downstream problems of industrialization from the first stages of development. Abolis gathers a panel of technologies to bring our clients’ projects to the highest scientific level while constantly integrating the industrial, economical and environmental constraints. From informatics to the fermentation process, discover our technology portfolio :
Advanced genetic tools
Our team works daily to improve and create new tools that allow us to carry out ever more complex genetic modifications. We use them to build, stabilize, equilibrate long metabolic pathways from sugar to product, and enhance Titer, Yield and Rate for industrial production. Thanks to them, we achieved breakthrough results for the most complex pathways ever done by metabolic engineering.
Innovative software tools
Our software team has developed our own proprietary portfolio of softwares to streamline and manage complex biotechnological workflows. All our data and bio-informatic and chemo-informatic competencies are being managed by a unique tool called AWSOME (Abolis Workflow SOlution for Metabolic Engineering). This integrated toolkit enables us to seach for novel metabolic pathways, enzymes and ensure the complete tracability of what we develop.
We are constantly working to increase the number of natural strains we can engineer by developing novel genetic tools and competences. Our moto is: combine the best of human engineering with the best of what Nature has already made for us.
As iterative follow up of our genetic manipulations, the new strains performances are validated in our robotic 48 cuve fermenter and then scale up to 20L fermentation in order to validate strains and bio-process in an environment highly relevant for industrial scale. For the pre-industrial scale, we partner with a short list of high end specialists for DSP and Scale-up.
Cutting edge analytics
Our analytical chemistry team is continuously developing new methods using cutting-edge mass spectrometry technologies to be able to analyze and compare the performance of our strains for the production of your molecule, side products, fluxes and health-state of the microbe.
We use robots to enable higher throughput strains construction and testing, while enabling the advantage of reproducibility and automated quality monitoring.